Anti-Heat Shock 27kDa Protein 1 (HPS27)(CPTC-HSPB1-2)

HSP27, also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature, as well as by estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSPs and mammalian -crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. Therefore, HSP27 may be useful in classifying various hormone sensitive tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Heat shock 27kDa protein; Estrogen-regulated 24kDa protein; Heat shock 25kDa protein 1; Heat shock 28kDa protein 1; Heat shock protein beta-1; HMN2B; Hsp25; Hsp28; HspB1; Stress-responsive protein 27 (SRP27)

41116161

Primary and secondary antibodies for multiple methodology
immunostaining detection application

HSPB1

3315

520973

P04792

Nucleus & cytoplasm

Mouse

Human

Recombinant human full-length protein

Heat Shock 27kDa Protein 1

Monoclonal

IgG1 κ

CPTC-HSPB1-2

Purified, with BSA

Tumor

Animal

Flow, intracellular (verified) | IHC, FFPE (verified) | WB (verified)

FC, IHC, FFPE, WB

MCF-7, HeLa cells; ~50% of Breast Carcinomas are positive for hsp27 especially those that are also positive for ER and/or PgR.

0.2 mg/mL

PBS, 0.05% BSA, 0.05% azide

27 kDa

Room temperature

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

2 years

Primary

https://biotium.com/product/hsp27-monoclonal-mouse-antibody-cptc-hspb1-2