IL-1F6 rabbit pAb

The protein encoded by this gene is a Cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. [provided by RefSeq, Nov 2015],

Interleukin-36 alpha (FIL1 epsilon;Interleukin-1 epsilon;IL-1 epsilon;Interleukin-1 family member 6;IL-1F6)

27179

Q9UHA7

Cytoplasm. Secreted. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion..

Rabbit

Human, Rat, Mouse,

The antiserum was produced against synthesized peptide derived from the Internal region of human IL36A. AA range:21-70

Polyclonal

IHC, IF, ELISA

1 year

1 mg/mL

IHC-p 1:50-200, ELISA 1:10000-20000

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.