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IL-2Rα rabbit pAb

CAT:ES5871-02Size:100 μLPrice:Ask for quotation

Availability:

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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This product ships without dry ice.

Description:

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. [provided by RefSeq, Nov 2009],

Synonyms:

IL2RA; Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD antigen CD25

Gene ID:

3559

UniProt:

P01589

Cellular Locus:

Membrane; Single-pass type I membrane protein.

Host:

Rabbit

Species Reactivity:

Human,Rat,Mouse,

Immunogen:

The antiserum was produced against synthesized peptide derived from human IL-2R alpha/CD25. AA range:223-272

Clonality:

Polyclonal

Validated Applications:

WB,IF,ELISA

Stability:

1 year

Concentration:

1 mg/mL

Dilution:

Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight:

55kD

Storage Conditions:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Picture:

Product Datasheet:

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