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IRAK-M rabbit pAb

CAT:ES4616-02Size:100 μLPrice:Ask for quotation
Availability:
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description:

This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010],

Synonyms:

IRAK3; Interleukin-1 receptor-associated kinase 3; IRAK-3; IL-1 receptor-associated kinase M; IRAK-M

Gene ID:

11213

UniProt:

Q9Y616

Cellular Locus:

Cytoplasm. Nucleus. In dendritic cells, translocates into the nucleus upon IL33 stimulation..

Host:

Rabbit

Species Reactivity:

Human,Rat,Mouse,

Immunogen:

The antiserum was produced against synthesized peptide derived from human IRAK3. AA range:491-540

Clonality:

Polyclonal

Validated Applications:

WB,IHC,IF,ELISA

Stability:

1 year

Concentration:

1 mg/mL

Dilution:

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight:

68kD

Storage Conditions:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Picture:
Image 1
Product Datasheet:

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