Kallistatin rabbit pAb

Function: Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. miscellaneous: Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity. PTM: The N-terminus is blocked. similarity: Belongs to the serpin family. subunit: Monomer and some homodimers. tissue specificity: Expressed by the liver and secreted in plasma.

SERPINA4; KST; PI4; Kallistatin; Kallikrein inhibitor; Peptidase inhibitor 4; PI-4; Serpin A4

5267

P29622

Secreted.

Rabbit

Human, Rat, Mouse,

The antiserum was produced against synthesized peptide derived from the Internal region of human SERPINA4. AA range:161-210

Polyclonal

WB, IHC, IF, ELISA

1 year

1 mg/mL

Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

47kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.