LT-β rabbit pAb

Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e. g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Lymphotoxin-beta (LT-beta;Tumor necrosis factor C;TNF-C;Tumor necrosis factor ligand superfamily member 3)

4050

Q06643

Membrane ; Single-pass type II membrane protein.

Rabbit

Human,Rat,Mouse,

Synthetic peptide from human protein at AA range: 41-90

Polyclonal

WB,IHC,IF,ELISA

1 year

1 mg/mL

IHC-p 1:50-200, ELISA 1:10000-20000,WB 1:500-2000

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.