MARCH4 rabbit pAb

MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al. 2004 [PubMed 14722266]). [supplied by OMIM, Apr 2010],

MARCH4; KIAA1399; RNF174; E3 ubiquitin-protein ligase MARCH4; Membrane-associated RING finger protein 4; Membrane-associated RING-CH protein IV; MARCH-IV; RING finger protein 174

57574

Q9P2E8

Golgi apparatus membrane ; Multi-pass membrane protein.

Rabbit

Human,Mouse

The antiserum was produced against synthesized peptide derived from human MARCH4. AA range:301-350

Polyclonal

IHC,IF,ELISA

1 year

1 mg/mL

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.