MARCKS rabbit pAb

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008],

MARCKS; MACS; PRKCSL; Myristoylated alanine-rich C-kinase substrate; MARCKS; Protein kinase C substrate; 80 kDa protein, light chain; 80K-L protein; PKCSL

4082

P29966

Cytoplasm, cytoskeleton. Membrane ; Lipid-anchor.

Rabbit

Human,Mouse,Rat

The antiserum was produced against synthesized peptide derived from human MARCKS. AA range:126-175

Polyclonal

WB,IF,ELISA

1 year

1 mg/mL

Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

31kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.