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MARH8 rabbit pAb
MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al. 2003 [PubMed 12582153]; Bartee et al. 2004 [PubMed 14722266]). [supplied by OMIM, Apr 2010],
220972
Q5T0T0
Cytoplasmic vesicle membrane ; Multi-pass membrane protein. Lysosome membrane ; Multi-pass membrane protein. Early endosome membrane ; Multi-pass membrane protein.
Rabbit
Human,Rat,Mouse,
Synthesized peptide derived from part region of human protein
Polyclonal
WB,ELISA
1 year
1 mg/mL
WB 1:500-2000 ELISA 1:5000-20000
32kD
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
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