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MMP-13 rabbit pAb

CAT:ES2804-02Size:100 μLPrice:Ask for quotation
Availability:
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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This product ships without dry ice.
Description:

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016],

Synonyms:

MMP13; Collagenase 3; Matrix metalloproteinase-13; MMP-13

Gene ID:

4322

UniProt:

P45452

Cellular Locus:

Secreted, extracellular space, extracellular matrix. Secreted.

Host:

Rabbit

Species Reactivity:

Human,Rat,Mouse,

Immunogen:

The antiserum was produced against synthesized peptide derived from human MMP-13. AA range:10-59

Clonality:

Polyclonal

Validated Applications:

WB,IHC,IF,ELISA

Stability:

1 year

Concentration:

1 mg/mL

Dilution:

Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.

Molecular Weight:

55kD

Storage Conditions:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Picture:
Image 1
Product Datasheet:

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