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Mouse Vinculin (VCL) ELISA Kit
Mouse Vinculin (VCL) ELISA Kit
Product Description:This Mouse Vinculin (VCL) ELISA Kit employs a two-site sandwich ELISA to quantitate VCL.
Reactivity: Mouse
Sample types: serum, whole blood, plasma and other biological fluids
Detection range: Please inquire
Sensitivity: Please inquire Quantitative Sandwich ELISA
Method of detection: Colorimetric
Storage: The unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.Shipping:Gel pack with blue ice.
In mammalian cells, vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Its sequence is 20-30% homologous to ?-catenin, which serves a similar function. Vinculin is a 117 kDa cytoskeletal protein with 1066 amino acids. The protein contains an acidic N-terminal domain and a basic C-terminal domain separated by a proline-rich middle segment. Vinculin consists of a globular head domain that contains binding sites for talin and ?-actinin as well as a tyrosine phosphorylation site, while the tail region contains binding sites for F-actin, paxillin and lipids.
This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.