MRGX1 rabbit pAb

Function: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G (alpha)q proteins are involved in the calcium-signaling pathway. similarity: Belongs to the G-protein coupled receptor 1 family. Mas subfamily. tissue specificity: Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.

MRGPRX1; MRGX1; SNSR3; SNSR4; Mas-related G-protein coupled receptor member X1; Sensory neuron-specific G-protein coupled receptor 3/4

259249

Q96LB2

Cell membrane; Multi-pass membrane protein.

Rabbit

Human, Rat, Mouse,

The antiserum was produced against synthesized peptide derived from human MRGX1. AA range:271-320

Polyclonal

WB, IHC

1 year

1 mg/mL

WB 1:500-2000;IHC-p 1:50-300

36kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.