MRP3 rabbit pAb

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008],

ABCC3; CMOAT2; MLP2; MRP3; Canalicular multispecific organic anion transporter 2; ATP-binding cassette sub-family C member 3; Multi-specific organic anion transporter D; MOAT-D; Multidrug resistance-associated protein 3

8714

O15438

Basolateral cell membrane ; Multi-pass membrane protein.

Rabbit

Human, Rat, Mouse,

The antiserum was produced against synthesized peptide derived from human ABCC3. AA range:971-1020

Polyclonal

WB, IHC

1 year

1 mg/mL

WB 1:500-2000;IHC-p 1:50-300

170kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.