MUC4 Antibody / Mucin-4

The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. MUC-4 transcripts have been detected in normal respiratory epithelium and lung. MUC-4 is a very specific (100%) and sensitive (90%) marker of lung adenocarcinomas and is negative for mesotheliomas. Reportedly, MUC-4 expression in invasive ductal carcinoma of the pancreas is an independent factor for poor prognosis.

Q99102

Mouse

Amino acids 1730-1864 from the human protein were used as the immunogen for this MUC4 antibody.

Monoclonal

IgG1 κ

IHC-P

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Store the MUC4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This MUC4 antibody is available for research use only.

Primary antibody

https://www.nsjbio.com/tds/muc4-antibody-muc4-3084-human-protein-microarray-specificity-validated-v7541