MYO15 rabbit pAb

This gene encodes an unconventional myosin. This protein differs from other myosins in that it has a long N-terminal extension preceding the conserved motor domain. Studies in mice suggest that this protein is necessary for actin organization in the hair cells of the cochlea. Mutations in this gene have been associated with profound, congenital, neurosensory, nonsyndromal deafness. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Read-through transcripts containing an upstream gene and this gene have been identified, but they are not thought to encode a fusion protein. Several alternatively spliced transcript variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008],

51168

Q9UKN7

Cell projection, stereocilium. Cytoplasm, cytoskeleton. Localizes to stereocilium tips in cochlear and vestibular hair cells..

Rabbit

Human, Mouse

Synthesized peptide derived from human protein . at AA range: 2990-3070

Polyclonal

IHC, IF

1 year

1 mg/mL

IHC-p 1:50-300

388kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.