Nanog P8 rabbit pAb

This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG. [provided by RefSeq, Sep 2009],

NANOGP8; Putative homeobox protein NANOGP8

388112

Q6NSW7

Nucleus.

Rabbit

Human, Rat, Mouse,

The antiserum was produced against synthesized peptide derived from human NANOGP8. AA range:51-100

Polyclonal

WB, IF, ELISA, IHC

1 year

1 mg/mL

WB 1:500-2000; IF/ICC 1:50-200;ELISA 1:2000-20000;IHC-p 1:50-200

35kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.