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Nesprin-3 rabbit pAb
Function: Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1/Plectin which can associate with the intermediate filament system. similarity: Belongs to the nesprin family. similarity: Contains 1 KASH domain. similarity: Contains 2 spectrin repeats. subcellular location: Located at the rough reticulum endoplasmic (RER) in some cells. subunit: Interacts with actin-binding domain of PLEC1/plectin.
SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3
161176
Q6ZMZ3
Nucleus outer membrane ; Single-pass type IV membrane protein. Nucleus envelope. Rough endoplasmic reticulum.
Rabbit
Human, Mouse
The antiserum was produced against synthesized peptide derived from human C14orf49. AA range:169-218
Polyclonal
WB, IF, ELISA
1 year
1 mg/mL
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
115kD
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
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