OCLN rabbit pAb

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1. 5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011],

100506658

Q16625

Cell membrane ; Multi-pass membrane protein. Cell junction, tight junction.

Rabbit

Human, Mouse, Rat

Synthesized peptide derived from part region of human protein. AA350-400

Polyclonal

WB IF, ELISA

1 year

1 mg/mL

WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.

57kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.