+1 (408)780-0908

PA26 rabbit pAb

CAT:ES5548-01Size:50 μLPrice:Ask for quotation

Availability:

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Shipping:

This product ships without dry ice.

Description:

This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],

Synonyms:

SESN1; PA26; SEST1; Sestrin-1; p53-regulated protein PA26

Gene ID:

27244

UniProt:

Q9Y6P5

Cellular Locus:

Nucleus. Cytoplasm.

Host:

Rabbit

Species Reactivity:

Human,Mouse,Rat

Immunogen:

The antiserum was produced against synthesized peptide derived from human SESN1. AA range:271-320

Clonality:

Polyclonal

Validated Applications:

WB,IHC,IF,ELISA

Stability:

1 year

Concentration:

1 mg/mL

Dilution:

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight:

57kD

Storage Conditions:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Picture:

Product Datasheet:

Loading PDF...