PDE10A rabbit pAb

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011],

PDE10A; cAMP and cAMP-inhibited cGMP 3'; 5'-cyclic phosphodiesterase 10A

10846

Q9Y233

Cytoplasm, cytosol.

Rabbit

Human, Rat

The antiserum was produced against synthesized peptide derived from human PDE10A. AA range:21-70

Polyclonal

WB, ELISA, IHC

1 year

1 mg/mL

WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000

75kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.