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PTH-rP rabbit pAb

CAT:ES8508-02Size:100 μLPrice:Ask for quotation

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description:

Parathyroid hormone like hormone (PTHLH) Homo sapiens The protein encoded by this gene is a member of the parathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in this gene are associated with brachydactyly type E2 (BDE2). Alternatively spliced transcript variants have been found for this gene. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone. [provided by RefSeq, Nov 2013],

Synonyms:

Parathyroid hormone-related protein (PTH-rP) (PTHrP) (Parathyroid hormone-like protein) (PLP) [Cleaved into: PTHrP[1-36]; PTHrP[38-94]; Osteostatin (PTHrP[107-139])]

Gene ID:

5744

UniProt:

P12272

Cellular Locus:

Cytoplasm. Nucleus. Secreted.

Host:

Rabbit

Species Reactivity:

Human, Rat, Mouse,

Immunogen:

The antiserum was produced against synthesized peptide derived from the Internal region of human PTHLH. AA range:101-150

Clonality:

Polyclonal

Validated Applications:

WB, IHC

Stability:

1 year

Concentration:

1 mg/mL

Dilution:

WB 1:500-2000;IHC-p 1:50-300

Molecular Weight:

25kD

Storage Conditions:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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