R4RL2 rabbit pAb

Function: May play a role in regulating axonal regeneration and plasticity in the adult central nervous system. PTM: Undergoes zinc metalloproteinase-mediated ectodomain shedding in neuroblastoma cells; where BRE is released as a full-length ectodomain and an N-terminal fragment containing the leucine-rich repeat (LRR) region of the protein. similarity: Belongs to the Nogo receptor family. similarity: Contains 8 LRR (leucine-rich) repeats. subcellular location: Localized to the surface of neurons, including axons. tissue specificity: Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid.

349667

Q86UN3

Cell membrane ; Lipid-anchor, GPI-anchor. Membrane raft. Cell projection, dendrite. Perikaryon. Cell projection, axon. Localized to the surface of neurons, including axons. Detected close to synapses, but is excluded from synapses..

Rabbit

Human, Rat, Mouse

Synthesized peptide derived from human protein . at AA range: 290-370

Polyclonal

WB, ELISA

1 year

1 mg/mL

WB 1:500-2000 ELISA 1:5000-20000

46kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.