SMC1B rabbit pAb

Structural maintenance of chromosomes 1B (SMC1B) Homo sapiens SMC1L2 belongs to a family of proteins required for chromatid cohesion and DNA recombination during meiosis and mitosis (3: Revenkova et al. 2001 [PubMed 11564881]). [supplied by OMIM, Mar 2008],

27127

Q8NDV3

Nucleus. Chromosome. Chromosome, centromere. Associates with chromatin. In prophase I stage of meiosis, localizes along the AE of synaptonemal complexes. In late-pachytene-diplotene, the bulk of protein dissociates from the chromosome arms probably because of phosphorylation by PLK, except at centromeres, where cohesin complexes remain. Remains chromatin associated at the centromeres up to metaphase II. At anaphase II, dissociates from centromeres, allowing chromosomes segregation (By similarity)..

Rabbit

Human,Rat,Mouse,

Synthesized peptide derived from human protein . at AA range: 110-190

Polyclonal

WB,ELISA

1 year

1 mg/mL

WB 1:500-2000 ELISA 1:5000-20000

135kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.