TNR21 rabbit pAb

This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013],

27242

O75509

Cell membrane ; Single-pass type I membrane protein.

Rabbit

Human, Mouse

Synthesized peptide derived from human protein . at AA range: 430-510

Polyclonal

WB, ELISA

1 year

1 mg/mL

WB 1:500-2000 ELISA 1:5000-20000

72kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.