Topoisomerase II alpha Antibody / TOP2A

This mAb recognizes an ~170kDa protein which is identified as Topoisomerase IIa, and shows no cross-reaction with Topoisomerase IIb or I. Topo IIa plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topo IIa is also implicated in drug resistance of tumor cells.

P11388

Mouse

Amino acids 1352-1493 from the human protein were used as the immunogen for this Topoisomerase II alpha antibody.

Monoclonal

IgG2b κ

IF, WB, IHC-P

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Store the Topoisomerase II alpha antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This Topoisomerase II alpha antibody is available for research use only.

Primary antibody

https://www.nsjbio.com/tds/topoisomerase-ii-alpha-antibody-top2a-1361-v3443