Anti-Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (TYRP1/1986), CF640R conjugate

This antibody reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death._x000D_
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Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_

5; 6 dihydroxyindole 2 carboxylic acid oxidase; 6-dihydroxyindole-2-carboxylic acid oxidase; Associated with iris pigmentation; CAS2; Catalase B (CATB); DHICA oxidase; Glycoprotein75 (GP75); Melanoma antigen gp75

41116161

Primary and secondary antibodies for multiple methodology
immunostaining detection application

TYRP1

7306

270279

P17643

Vesicular

Mouse

Human

A recombinant fragment (around aa 257-377) of human TYRP1 protein (exact sequence is proprietary)

Tyrosinase Related Protein-1

Monoclonal

IgG2b κ

TYRP1/1986

CF640R

Tumor

Animal

IHC, FFPE (verified)

IHC, FFPE

Cancer

SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells. Human Skin or Melanoma.

0.1 mg/mL

PBS, 0.1% BSA, 0.05% azide

75 kDa

Room temperature

4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

2 years

Primary

https://biotium.com/product/tyrosinase-related-protein-1-monoclonal-mouse-antibody-tyrp1-1986