Anti-UPK3A (Uroplakin 3A)(Rabbit PAb), CF594 conjugate

Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer._x000D__x000D_Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

UP3a, UPIIIA, UPK3A, Uroplakin III (UPIII), Uroplakin3A

41116161

Primary and secondary antibodies for multiple methodology
immunostaining detection application

UPK3A

7380

632787

O75631

Plasma membrane

Rabbit

Human

A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A

UPK3A

Polyclonal

IgG

PAb

CF594

Tumor

Animal

WB (verified)

WB

Cancer

HEK293 cells or bladder carcinoma

0.1 mg/mL

PBS, 0.1% BSA, 0.05% azide

~30 kDa

Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 1-2 ug/mL|Flow Cytometry 0.5-1 ug/million cells/0.1 mL|Western blotting 0.5-1 ug/mL|Optimal dilution for a specific application should be determined by user

Room temperature

4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

2 years

Primary

https://biotium.com/product/monoclonal-anti-upk3a-uroplakin-3a-rabbit-pab