Uroplakin 1A Antibody / UPK1A

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.

O00322

Mouse

A portion of amino acids 114-173 was used as the immunogen for the UPK1A antibody.

Monoclonal

IgG2b κ

ELISA

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Aliquot the UPK1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This UPK1A antibody is available for research use only.

Primary antibody

https://www.nsjbio.com/tds/upk1a-antibody-upk1a-2923-v9130