Uroplakin 1B Antibody / UPK1B

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. UPK1B is expressed by terminally differentiated urothelial cells.

O75841

Mouse

A recombinant human partial protein (amino acids 109-229) was used at the immunogen for this UPK1B antibody.

Monoclonal

IgG2b κ

IHC-P

Purified

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Store the UPK1B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This UPK1B antibody is available for research use only.

Primary antibody

https://www.nsjbio.com/tds/upk1b-antibody-upk1b-3081-v8152