Anti-YBX1 / Y-box Binding Protein 1 / YB-1 (Tumor Biomarker)(rYBX1/2430), CF647 conjugate

The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000 full-length human proteins. Y-box binding protein-1 (YBX1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus, YBX1 protein orchestrates transcription of proliferation-related genes, whereas in the cytoplasm it associates with mRNA and directs translation. In human tumor entities, such as breast, lung and prostate cancer, cellular YBX1 expression indicates poor clinical outcome, suggesting that YBX1 is an attractive marker to predict patients' prognosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

BP-8; CSDA2; CSDB; DBPB; MDR-NF1; NSEP-1; NSEP1; YB-1; YB1

41116161

Primary and secondary antibodies for multiple methodology
immunostaining detection application

YBX1

4904

473583

P67809

Nucleus & cytoplasm

Mouse

Human

Recombinant human full-length YBX1 protein

Y-box Binding Protein 1 | YB-1 | YBX1

Recombinant Monoclonal

IgG1 κ

rYBX1/2430

CF647

Tumor

Animal

IHC, FFPE (verified)

IHC, FFPE

MCF-7, HEK293 or PC12 cells. Prostate, Breast or Lung Carcinoma.

0.1 mg/mL

PBS, 0.1% BSA, 0.05% azide

36 kDa

Room temperature

4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

2 years

Primary

https://biotium.com/product/ybx1-y-box-binding-protein-1-yb-1-recombinant-monoclonal-mouse-antibody-rybx1-2430