ZHX3 Antibody

Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).

Q9H4I2

Mouse

Recombinant full-length human ZHX3 protein was used as the immunogen for the ZHX3 antibody.

Monoclonal

IgG2b

ELISA, IP, WB, FACS

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Aliquot the ZHX3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This ZHX3 antibody is available for research use only.

Primary antibody

https://www.nsjbio.com/tds/zhx3-antibody-pcrp-zhx3-1d11-v8872