MMP2 Antibody

It recognizes a protein of 72kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.

P08253

Mouse

Recombinant human protein was used as the immunogen for the Matrix metalloproteinase 2 antibody.

Monoclonal

IgG2b κ

IHC-P

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Aliquot the Matrix metalloproteinase 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This Matrix metalloproteinase 2 antibody is available for research use only.