STING1 Antibody / TMEM173 / ERIS / MITA

TMEM173 (transmembrane protein 173), also called STING (Stimulator of interferon genes protein), ERIS and MITA, is a 379 amino acid protein encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Q86WV6

Mouse

A recombinant partial protein sequence (within amino acids 190-290) from the human protein was used as the immunogen for the Stimulator of interferon genes protein antibody.

Monoclonal

IgG κ

IHC-P

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Aliquot the Stimulator of interferon genes protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This Stimulator of interferon genes protein antibody is available for research use only.