CDX2 Recombinant Antibody

The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

Q99626

Mouse

A synthetic peptide from human CDX2 protein was used as the immunogen for the recombinant Caudal Type Homeobox 2 antibody.

Monoclonal

IgG1 κ

Recombinant

IHC-P

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Aliquot the recombinant Caudal Type Homeobox 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This recombinant Caudal Type Homeobox 2 antibody is available for research use only.