Histone H3.3 Antibody (H3F3A)

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene for histone H3-MeK9 is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

P84243

Rabbit

This Histone H3.3 antibody was produced from rabbits immunized with a KLH conjugated synthetic peptide selected from the K9 region of human H3F3A.

Polyclonal

Ig

WB, IHC, FACS, ELISA

Antigen affinity purified

In 1X PBS pH 7.4 with 0.09% sodium azide

Aliquot the Histone H3.3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This Histone H3.3 antibody is available for research use only.