dsDNA Recombinant Antibody / Double Stranded DNA

This mAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This mAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells.Double Stranded deoxyribonucleic acid (ds DNA) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds between complementary base pairs.

Not Applicable

Mouse

Burkitt's cell nuclei were used as the immunogen for the Double Stranded DNA antibody.

Monoclonal

IgG2b κ

Recombinant

IHC-P

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Aliquot the Double Stranded DNA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This Double Stranded DNA antibody is available for research use only.