Peroxiredoxin 3 Antibody (PRDX3)

Peroxiredoxin 3 is a mitochondrial protein belonging to the AhpC/TSA family. Expression of PRDX3 is induced by MYC and is reduced in c-myc -/- cells. Chromatin immunoprecipitation analysis spanning the entire PRDX3 genomic sequence revealed that MYC binds preferentially to a 930-bp region surrounding exon 1. Results using mitochondria-specific fluorescent probes demonstrated that Peroxiredoxin 3 is essential for maintaining mitochondrial mass and membrane potential in transformed rat and human cells.

P30048

Rabbit

Amino acids 239-256 (TIKPSPAASKEYFQKVNQ-human) were used as the immunogen for this Peroxiredoxin 3 antibody.

Polyclonal

IgG

WB, IHC-P, IF, FACS

Antigen affinity purified

0.5mg/ml if reconstituted with 0.2ml sterile DI water

The lyophilized Peroxiredoxin 3 antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freezing and thawing.

This Peroxiredoxin 3 antibody is available for research use only.