This antibody recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to ErbB2, -3 -4 or HER2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head/neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

The immunizing protein for this antibody was recombinant human EGFR.

FACS, IF

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Store the EGFR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This EGFR antibody is available for research use only.

https://www.nsjbio.com/get_image.php?catalog_no=V2105-100UG&type=image1

https://www.nsjbio.com/tds-pdf/egfr-antibody-gfr450-v2105