CD28 Antibody

This antibody recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical Tcell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing Tcells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. it is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.

Mouse

Recombinant human protein was used as the immunogen for this CD28 antibody.

Monoclonal

IgG1 κ

FACS, IF, Functional studies

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Store the CD28 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This CD28 antibody is available for research use only.