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CD47 Recombinant Antibody / IAP / Integrin Associated Protein

CAT:V9335-20UGSize:20 µgPrice:Ask for quotation

Availability:

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Shipping:

This product ships with dry ice.

Description:

This antibody reacts with Ig domain of CD47/Integrin Associated Protein/IAP protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. It plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47/IAP may play a role in membrane transport and/or integrin dependent signal transduction.

UniProt:

Q08722

Host:

Mouse

Immunogen:

Recombinant full-length human protein was used as the immunogen for the recombinant Integrin Associated Protein antibody.

Clonality:

Monoclonal

Isotype:

IgG1 κ

Type:

Recombinant

Applications:

IHC-P

Format:

Purified

Buffer:

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution:

Aliquot the recombinant Integrin Associated Protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations:

This recombinant Integrin Associated Protein antibody is available for research use only.

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