KRT8 Recombinant Antibody / Cytokeratin 8

Cytokeratin 8 (also called CK8, Keratin 8 and KRT8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium.

P05787

Rabbit

Recombinant full-length human KRT8 protein was used as the immunogen for the recombinant Keratin 8 antibody.

Monoclonal

IgG

Recombinant

WB, IHC-P

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Aliquot the recombinant Keratin 8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This recombinant Keratin 8 antibody is available for research use only.