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SMAD2 Antibody

CAT:F50345-0.4MLSize:0.4 mLPrice:Ask for quotation

Availability:

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Shipping:

This product ships with dry ice.

Description:

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. [UniProt]

UniProt:

Q15796

Host:

Rabbit

Immunogen:

A portion of amino acids 97-125 from the human protein was used as the immunogen for this SMAD2 antibody.

Clonality:

Polyclonal

Isotype:

Applications:

IF, WB, FACS, ELISA

Format:

Antigen affinity purified

Buffer:

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution:

Aliquot the SMAD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations:

This SMAD2 antibody is available for research use only.

Product Picture:

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