Estrogen Receptor Antibody (alpha, isoform 4)

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

P03372-4

Rabbit

A portion of amino acids 271-300 from the human protein was used as the immunogen for this Estrogen Receptor antibody (isoform 4).

Polyclonal

Ig

WB, IF, ELISA

Antigen affinity purified

In 1X PBS, pH 7.4, with 0.09% sodium azide

Aliquot the Estrogen Receptor antibody (isoform 4) and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This Estrogen Receptor antibody (isoform 4) is available for research use only.