Biotinylated domestic pig Serum Albumin Protein, His,Avitag™ (MALS verified)

Biotinylated domestic pig Serum Albumin, His,Avitag (DSA-D82E1) is expressed from human 293 cells (HEK293). It contains AA Arg 19 - Ala 607 (Accession # A2THZ2-1).

serum albumin (SA) is also known as ALB, which is the main protein of plasma and has a good binding capacity for water,Ca2+,Na+,K+,fatty acids,hormones, bilirubin and drugs.The main function of SA is the regulation of the colloidal osmotic pressure of blood. As Major zinc transporter in plasma, SA typically binds about 80% of all plasma zinc. A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood. Defects in serum albumin can cause familial dysalbuminemic hyperthyroxinemia which is a form of euthyroid hyperthyroxinemia that is due to increased affinity of serum albumin for T4. It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 71.1 kDa. The protein migrates as 66-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Arg 19 - Ala 607

HEK 293

Serum Albumin

Biotin-labeled

C-10×His & C-Avi

Domestic pig

-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.

1.0 EU per μg

95%

Powder

PBS, pH7.4

Trehalose

71.1 kDa

Room Temperature

-20°C