Cytochrome p450 2C19 Antibody / CYP2C19

CYP2C19 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within its gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes.

P33261

Rabbit

A portion of amino acids 82-108 from the human protein was used as the immunogen for the Cytochrome p450 2C19 antibody.

Polyclonal

Ig

IF, WB, IHC-P

Purified

In 1X PBS, pH 7.4, with 0.09% sodium azide

Aliquot the Cytochrome p450 2C19 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This Cytochrome p450 2C19 antibody is available for research use only.