CFH Antibody / Complement factor H

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

P08603

Rabbit

A portion of amino acids 751-780 from the human protein was used as the immunogen for the Complement factor H antibody.

Polyclonal

IgG

IHC-P, WB, IF

Purified

In 1X PBS, pH 7.4, with 0.09% sodium azide

Aliquot the Complement factor H antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This Complement factor H antibody is available for research use only.