Bax Antibody

Recognizes a protein of 21kDa, identified as the Bax protein. This mAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.

Q07812

Mouse

Recombinant full-length human protein was used as the immunogen for the Bax antibody.

Monoclonal

IgG1 κ

FACS, IHC-P

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Store the Bax antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This Bax antibody is available for research use only.