CD11b Recombinant Antibody / MAC-1

The ITGAM gene encodes the integrin alpha M chain, also called CD11b and MAC-1. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [RefSeq]

P11215

Rabbit

A synthetic peptide specific to human CD11b / ITGAM was used as the immunogen for the CD11b antibody.

Monoclonal

IgG

Recombinant

IHC-P, WB

Purified

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Store the CD11b antibody at -20oC.

This CD11b antibody is available for research use only.