Claudin 2 Antibody (CLDN2)

Claudin-2 is expressed in cation-leaky epithelia such as that of the kidney proximal tubule. Mice that are deficient in the protein have reduced reabsorption of Na+ in the proximal tubule, consistent with a role in paracellular transport. Similar results have been obtained with cultured cells, as overexpression in CLDN2 lacking cells leads to increase of permeability for small cations. Furthermore, CLDN2 has been shown to form paracellular channels for water. [Wiki]

P57739

Rabbit

A portion of amino acids 135-164 from the human protein was used as the immunogen for this Claudin 2 antibody.

Polyclonal

Ig

WB, IHC, ELISA

Antigen affinity purified

In 1X PBS, pH 7.4, with 0.09% sodium azide

Aliquot the Claudin 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This Claudin 2 antibody is available for research use only.