Lamin B2 Antibody

Lamin B2, also called LMNB2, is a protein associated with laminopathies. The LMNB2 gene is mapped to the G-negative subtelomeric band p13.3 of chromosome 19 by in situ hybridization. Model organisms have been used in the study of Lamin B2 function. A conditional knockout mouse line, called Lmnb2, was generated as part of the International Knockout Mouse Consortium program-a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. A highly sensitive procedure about mapping the start site of DNA replication in a 13.7-kb region of human chromosome 19 coding for lamin B2 is developed for the identification of the origin of bidirectional DNA synthesis in single-copy replicons of mammalian cells.

Q03252

Rabbit

Amino acids 580-597 (EEDLFHQQGDPRTTSRGC) were used as the immunogen for this Lamin B2 antibody (100% homologous in human, mouse and rat).

Polyclonal

IgG

WB, IHC-P, IHC-F

Antigen affinity purified

0.5mg/ml if reconstituted with 0.2ml sterile DI water

The lyophilized Lamin B2 antibody can be stored at 4oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freezing and thawing.

This Lamin B2 antibody is available for research use only.